The ICT Safe's mission is to reduce transportation-related fatalities and serious injuries in the WAMPO region by implementing the Comprehensive Safety Action Plan (CSAP). It includes a diverse range of stakeholders involved in education, engineering, enforcement, and emergency response. ICT Safe will review Behavioral Safety Grant applications, as well as assume other responsibilities at the discretion of its members. Such additional responsibilities might include developing policy proposals for state and local governments, creating safety-policy toolkits, or disseminating information.

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ICT Safe is an overarching coalition with several smaller entities under its umbrella. The Active Transportation Committee and Drive Safe Sedgwick now meet as committees of ICT Safe.